I'm getting random pauses in gameplay of around one second, this is most noticeable when going into a new room and just before your character speaks.

You can see this in action quite easily in the very first mission as you change rooms, although it does not happen every single time.

I'm playing with full detail with exception of level 4 shadows, I've tried turning ALL detail and graphics off but the issue remains exactly the same.  It is very distracting to have this happen as much as it does.

Using Windows 10 64bit, 32gig Ram, i7 6700k processor, Nvidia Geforce 980ti driver - 398.11 WHQL (latest). XBOX One controller.